Lionheart Health Research Portfolio
Mobile-friendly master table—79 programs. Second Heart Assist™ removed.
Status:
✅ Results reported ·
🟢 Active/enrolling ·
🟡 Planned/preparing ·
🔵 Development/preclinical ·
🟣 Patent/research platform
Skin, Hair and Sexual Health
| # |
Program |
Focus · Status |
| 1 |
SkinStim Plus™ |
Skin regeneration, collagen, elasticity and tone. ✅ Pilot results reported; expansion planned. |
| 2 |
HairCell Plus™ |
Hair density, follicle regeneration and scalp health. ✅ Pilot results reported; expansion planned. |
| 3 |
Hair Repigmentation |
Natural hair-color restoration. 🟣 Patent/preclinical stage. |
| 4 |
ErectiStim Plus™ |
Erectile function, circulation and male sexual health. ✅ Five studies reported. |
| 5 |
FemStim Plus™ |
Female sexual wellness, circulation and sensitivity. 🟡 Expanded study planned. |
| 6 |
TestiStim Plus™ |
Testosterone management, testicular function and fertility. ✅ Pilot case reported; expansion planned. |
| 7 |
Stem Cell Bra™ / BreastStim™ |
Breast-tissue augmentation and vascularization. ✅ Animal and pilot safety work reported; efficacy study planned. |
Joint, Bone, Pain and Nerves
| # |
Program |
Focus · Status |
| 8 |
OrthoStim Plus™ |
Joint pain, cartilage, mobility and osteoarthritis. ✅ Pilot results reported; expansion planned. |
| 9 |
OrthoStim PDA+™ |
Pentadeca Arginate with bioelectric and regenerative joint therapies. 🟡 New study arm announced. |
| 10 |
BoneStim Plus™ |
Bone density, healing and osteoporosis. 🟡 Multimodality study launched/planned. |
| 11 |
BMP9/OPG/Klotho Bone Study |
Increase bone formation and reduce bone loss. 🟣 Translational stage. |
| 12 |
Osteocalcin Expression Study |
Bone, brain, metabolic and sexual health. 🟣 Patent/preclinical stage. |
| 13 |
PainStim Plus™ |
Chronic pain, Klotho activation and neuromodulation. 🔵 Investigational platform. |
| 14 |
NerveStim Plus™ |
Peripheral-nerve repair and functional recovery. 🔵 Clinical-research platform launched. |
| 15 |
Neuropathy Relief Study |
Neuropathy, circulation, Klotho and regenerative support. 🟡 Study announced. |
| 16 |
SpineStim Plus™ |
Spinal-cord injury and neuromuscular recovery. 🔵 Early research stage. |
Brain and Mental Health
| # |
Program |
Focus · Status |
| 17 |
DepressiStim™ |
Depression, mood and stress via Brain Band Plus™. ✅ Pilot results reported. |
| 18 |
Brain-N-Hance™ |
Cognition, attention and executive function. ✅ Pilot results reported. |
| 19 |
MemoryStim™ |
Memory preservation and improvement. 🟡 Pilot study planned. |
| 20 |
CerebraCell™ |
Stroke and traumatic-brain-injury recovery. 🟡 Study preparing/planned. |
| 21 |
CerebraCell™ 60-Protein Study |
Regenerative protein targets plus Klotho-expressing cells. 🟣 Patent/translational stage. |
| 22 |
Menin Brain Study |
Menin expression for cognition and brain aging. 🟣 Patent/preclinical stage. |
| 23 |
Klotho Epilepsy Study |
Seizures, neuroinflammation and brain-injury reduction. 🟡 Translational study proposed. |
| 24 |
Digital Brain Wellness Study |
Digital testing, training and Brain Band support. 🟢 Expanded protocol. |
Eyes, Hearing and Dental Health
| # |
Program |
Focus · Status |
| 25 |
EyeCell Plus™ |
Vision improvement and retinal/optic-tissue support. ✅ Preliminary results reported. |
| 26 |
EyeCell™ Phase II |
Macular-degeneration stabilization or improvement. 🟡 Advancing toward Phase II. |
| 27 |
EyeCell E-Stent™ |
Retinal, optic-nerve and eye-pressure modulation. 🔵 Implant development. |
| 28 |
EyeCell Skaphor™ |
Eye fatigue and screen-related visual wellness. 🔵 Prospective study arm. |
| 29 |
EarCell Plus™ |
Hearing improvement and auditory-tissue recovery. 🟡 Combination study planned. |
| 30 |
Wnt-Signaling Study |
Hair, hearing, joints and longevity. 🟣 Patent/preclinical stage. |
| 31 |
DentaCell™ |
AI-guided regenerative dentistry and periodontal health. 🟣 Patent/research stage. |
| 32 |
ImplantStim™ |
Faster dental-implant healing and integration. 🟡 OUS pilot preparing to enroll. |
| 33 |
OrthodontiCell™ IL-1β/PGE2 |
Accelerated orthodontic tooth movement. 🟣 Patent/development stage. |
| 34 |
ArchStim™ |
Dental-arch expansion, stability and breathing. 🔵 Development stage. |
Bladder, Kidney, Liver, Gut and Pancreas
| # |
Program |
Focus · Status |
| 35 |
BladderCell™ / B-Alive™ |
Leakage, urgency and bladder control. ✅ Brazil clinical results reported. |
| 36 |
PelvicStim™ |
Pelvic neuromuscular and bladder function. 🟡 Expanded study planned. |
| 37 |
Implantable Bladder Therapy |
Long-term localized bladder stimulation. 🔵 Implant development. |
| 38 |
KidneyCell Plus™ |
Kidney function, CKD and Klotho restoration. ✅ Related human data reported; further study planned. |
| 39 |
LiverCell Plus™ |
Liver regeneration, metabolism and fatty-liver health. 🔵 Preclinical stage. |
| 40 |
PancreaCell Plus™ |
Diabetes and pancreatic/islet support. 🔵 Large-animal research planned. |
| 41 |
Second Brain Plus™ |
Gut health, microbiome, motility and gut–brain signaling. 🟡 Pilot study planned. |
| 42 |
InStim Plus™ |
Inflammation modulation and possible IBD applications. ✅ Pilot case reported; expansion planned. |
| 43 |
HGF/Klotho-Up™ |
HGF expression for muscle, liver, nerve and systemic regeneration. 🟢 Studies launched. |
Heart, Vascular and Lung Health
| # |
Program |
Focus · Status |
| 44 |
PressureStim Plus™ |
Blood-pressure modulation and vascular function. ✅ Pilot and independent results reported. |
| 45 |
Arterial-Aging Study |
PressureStim, BodStim, electro-acupuncture and Klotho-Up. 🟡 Multimodality program. |
| 46 |
VascuStim Plus™ |
Wound healing, circulation and tissue salvage. ✅ Results reported; new studies launched. |
| 47 |
RegenaLung Plus™ |
Lung regeneration, breathing and inflammation. 🔵 Preclinical/partnership stage. |
| 48 |
BioLeonhardt Plus™ |
Myocardial regeneration and heart recovery. 🔵 Large-animal development. |
| 49 |
MyoCell™–BioLeonhardt™ |
Cell-based heart-regeneration research. 🔵 Translational program. |
| 50 |
Cardiac Multi-Protein Study |
TBX20, PITX2, MEIS1 and pro-ANP/NPPA. 🔵 Preclinical/translational stage. |
| 51 |
BioPace™ |
Biological alternative to electronic cardiac pacing. 🔵 Preclinical/translational stage. |
| 52 |
Valvublator Plus™ |
Heart-valve regeneration and remodeling. 🔵 Large-animal study program. |
| 53 |
Living Muscle Pump™ / AortaCell™ |
Contractile myografts around the aorta and arteries. 🔵 Preclinical development. |
| 54 |
AortaCell AI™ |
AI MRI analysis for aneurysm detection and monitoring. 🔵 Imaging-platform development. |
| 55 |
BodStim™ for Heart Failure |
Muscle function and exercise capacity. 🟡 Lionheart-specific study proposed. |
Cancer and Immune Health
| # |
Program |
Focus · Status |
| 56 |
CancerCell™ |
Tumor-specific bioelectric treatment. ✅ Initial animal feasibility work reported; additional study planned. |
| 57 |
BodStim™ for Cancer |
Muscle, mobility and treatment-tolerance support. 🟡 Supportive-care research concept. |
| 58 |
Thymulin Expression Study |
Immune aging, inflammation and cancer-support research. 🟣 Patent/preclinical stage. |
Healthspan and Longevity
| # |
Program |
Focus · Status |
| 59 |
Lionheart Klotho-Up™ |
Muscle, brain, immunity and biological aging. 🟢 Human enrollment announced. |
| 60 |
BodStim™ for Healthspan |
Strength, lean mass, metabolism, mobility and Klotho. ✅ Human results reported. |
| 61 |
Lionheart Octopus™ |
Refillable biologic delivery plus organ-specific stimulation. 🔵 Preclinical platform. |
| 62 |
MitoCell™ / PC-Up™ |
Mitochondrial membranes, energy and mitophagy. 🟣 Research/patent program. |
| 63 |
OSER1 Longevity Study |
OSER1 expression for healthspan. 🟣 Patent/preclinical stage. |
| 64 |
SIRT6 Longevity Study |
DNA repair, metabolism and healthy aging. 🟣 Patent allowance; validation needed. |
| 65 |
FOXO3/AMPK/mTOR Study |
Autophagy, nutrient sensing and longevity. 🟣 Patent/preclinical stage. |
| 66 |
HMGB1 Study |
Regeneration, repair and stem-cell homing. 🟣 Patent/preclinical stage. |
| 67 |
Multi-Protein Expression Study |
Coordinated regulation of over 60 regenerative proteins. 🔵 Platform-wide research. |
| 68 |
Veterinary Bioelectric Study |
Animal mobility, recovery and performance. 🔵 Veterinary-development platform. |
Bioelectric-Enhanced Biologics
| # |
Program |
Focus · Status |
| 69 |
Enhanced Peptides |
Peptide uptake, retention and targeting. 🟣 Patent-pending platform. |
| 70 |
Enhanced Exosomes |
Exosome production, cargo, delivery and retention. 🟣 Research/patent program. |
| 71 |
Enhanced Stromal Fraction |
Cell activation, homing and tissue repair. 🔵 Translational platform. |
| 72 |
Enhanced Stem Cells |
Cell survival, homing and protein release. 🔵 Preclinical/translational platform. |
